![]() ![]() Affinity prediction of the compound to bind at the enzyme involved in several metabolic drug pathways.Ĭytochrome P450 CYP2D6 classification. With this you can easily tailor your filters for particular compound features andįurthermore, infiniSee supports the Optribrium expansion to predict a variety of important ADME parameters for further compound assessment:Ĭytochrome P450 CYP2C9 pK i prediction. You can also calculcate and filter for following numbers: odd torsions, heavy atoms, (aromatic) rings, aromatic atoms, nitrogen and oxygen atoms, halogens, stereo centers, stereo bonds, and rotatble bonds. InfiniSee can calculate and predict following parameters of a molecule that can be further used for filtering steps and compound assessment: HYDE-based (Lipophilic) ligand efficacy (LE/LLE), molecular weight, logP, total polar surface area (TPSA) of a compound, H-bonds, H-bond acceptors and donators, heavy atoms, aromatic rings, maximum ring size, total charge, and presence of covalent warheads. ![]() Important note: In order to run the Analog Hunter infiniSee requires the latest versions of the Chemical Spaces (as of March 8 th).įor older versions and an elaborate changelog please visit here. The colorful depiction helps users to understand the fingerprint alignment of the building block substructures to the query molecule to spot areas of high similarity and differences. Running the SpaceLight algorithm, Analog Hunter retrieves close analogs to a query compound from Chemical Spaces based on Tanimoto molecular fingerprint similarity. ![]() A powerful tool to spot frequent and unique patterns to enrich the chemical diversity for subsequent purposes.įurthermore, visual highlighting is introduced to the Analog Hunter. Version 5.1 introduces the well-know Bemis-Murcko scaffold and skeleton clustering to the Analyzer Mode which augments the compound selection and prioritization process: Given a set of molecules, infiniSee calculates prominent molecular motifs which can be used to group compounds into subsets. Time to experience the thrill of the hunt with infiniSee 5 - Artemis! ![]()
0 Comments
![]() ![]() Jeff Vogel, the man responsible for this game, has spent over a decade now crafting well thought-out, complex, turn-based RPGs for PCs and Macs, aiming at the enthusiasts of the genre. "Anybody who pines for the days of the older, massive classics and decries the state of the new streamlined, big-budget RPGs needs to put their money where their mouth is and buy this game. "Avadon: The Black Fortress is easily one of the best RPGs you can buy. Strong story and characters, great combat, excellent quests, addictive loot and leveling and high replayability." - Inside Mac Games "In the end, Avadon: The Black Fortress has everything a good RPG needs. Huge adventure with lots of replay value. ![]() Use enchanted crystals to make your artifacts even more powerful. Your choices will change the world.ĭozens of side quests, hidden dungeons, and secrets to discover. ![]() Uncover the fascinating history of Avadon and the land of Lynaeus. ![]() Experience an exciting fantasy role-playing adventure and battle a conspiracy to destroy your people.Įpic fantasy role-playing adventure in an enormous and unique world.įour different character classes, with dozens of unique spells and abilities. As a servant of the Black Fortress, your word is Law. You will serve the keep of Avadon, working as a spy and warrior to fight the enemies of your homeland. Experience huge adventures, cunning foes, hundreds of magic artifacts to find, and countless enemies of your people to hunt down.Īvadon HD is the first chapter in a new, epic fantasy saga. Avadon: The Black Fortress HD is an epic, old school fantasy role-playing adventure, with a fascinating story and 40+ hours of gameplay. ![]() ![]() ![]() You are able to perform a search based on the attribute tag, value or both at the same time. The application allows you to find attributes inside the document. You can also toggle to view file meta information (the Media Header). With a file a file open, you get to view the tag, attribute name and values. All the found files are then displayed in a list. It enables you locate files using a simple file browser embedded into the main window. It displays a user-friendly interface that allows you to easily locate and open the files. ![]() It’s a lightweight application that enables you to open, view and edit DICOM files. ![]() For this, DICOM Editor Tool is designed.īefore you can install the application, you need to make sure that you have the latest definitions on your computer. To be able to view and interpret the data information that lies in them you first of all need an application that is capable of opening that format. DICOM or Digital Imaging and Communications in Medicine documents are files that are used to store data in medical imaging. ![]() ![]() ![]() Create Windows To Go Workspace Directly from an ISO/WIM/ESD/SWM/VHD File or a CD/DVD Drive.It allows you to install and run fully-functional Windows on an external hard drive or USB flash drive, so you can carry this portable Windows USB drive anywhere and use it on any computer. WinToUSB Enterprise by EasyUEFI is so easy and efficient with just a few simple steps and a few minutes, you can create your first portable Windows 10/8/7 directly from an ISO, WIM, ESD, SWM, VHD, VHDX image file, or a CD/DVD drive, or you can use it to clone an existing Windows OS installation (Windows 7 or later) to a USB drive as portable Windows. ![]() This powerful tool allows you to easily install Windows on a USB drive, making it a convenient option for those looking to create a portable version of Windows. Overview of WinToUSBĪre you looking for an easy way to install Windows on a USB drive? EasyUEFI WinToUSB Professional is here to help. Free Download WinToUSB Enterprise Enterprise / Professional / Technician for Windows PC (also called Windows To USB) is the best free Windows To Go Creator, which allows you to install and run a fully-functional Windows operating system on an external hard drive or a USB flash drive. ![]() |
Details
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |